The Jiggins Lab Webpage

Elizabeth Duxbury

Research Interests

I am broadly interested in host-pathogen coevolution and life history evolution. My current research focuses on the intriguing paradox of why genetic variation in host susceptibility to infection is maintained and the impact of the arms race between host and pathogen on infection susceptibility. I am also interested in uncovering the genetic basis of resistance to pathogens and possible wider implications for the capacity of pathogens to host-shift. I work with Drosophila species and their RNA sigma viruses, to address these questions, using large-scale quantitative genetics assays and molecular tools.

Education and Employment

2016-present: Post-Doctoral Research Associate, Department of Genetics, University of Cambridge

2012-2016: PhD Student, School of Biological Sciences, University of East Anglia, BBSRC Norwich Research Park Doctoral Training Partnership studentship

March-July 2014: Postgraduate Fellow, Parliamentary Office of Science and Technology, Westminster, London

2011-2012: MSc in Entomology (Distinction), Imperial College London

2008-2011: BSc (Hons) in Natural Sciences, University of Bath

July-Sept 2010: Summer Studentship, Apoptosis and Proliferation Control Laboratory, London Research Institute, Cancer Research UK, Lincoln’s Inn Fields, London


2014: First Prize Richard Warn Memorial Award for talk at the UEA Biological Sciences Research Colloquium


Duxbury, E.M.L., Rostant, W.G. & Chapman, T. (2017) Manipulation of feeding regime alters sexual dimorphism for lifespan and reduces sexual conflict in Drosophila melanogaster. Proceedings of the Royal Society B: Biological Sciences, 284: 20170391. doi: 10.1098/rspb.2017.0391 [PDF]

Hunt, V.L., Zhong, W., McClure, C.D., Mlynski, D.T., Duxbury, E.M.L., Keith Charnley, A., Priest, N.K. (2016) Cold-seeking behaviour mitigates reproductive losses from fungal infection in Drosophila. Journal of Animal Ecology, 85: 178-186. doi: 10.1111/1365-2656.12438

Border, P. & Duxbury, E. (2014) GM crops and regulation, POSTnote 482. Parliamentary Office of Science and Technology, UK Parliament: Westminster, London, UK.

Duxbury, E.M.L., Mohorianu, I., Chapman, T. (in prep.) The transcriptional basis of evolved life history responses to feeding regime manipulation in the fruit fly, Drosophila melanogaster.

Duxbury, E.M.L. & Chapman, T. (in prep.) Effects of sustained activity level manipulation on the lifespan of fruit fly, Drosophila melanogaster.