The Jiggins Lab Webpage



Palmer, WJ, Duarte, A, Schrader, M, Day, JP, Kilner, R, Jiggins, FM 2016 A gene associated with social immunity in the burying beetle Nicrophorus vespilloides. Proc. R. Soc. B. 283: 20152733 [PDF]

Cao, C, Magwire, MM, Bayer, F and Jiggins, FM 2015 A Polymorphism in the processing body component Ge-1 Controls Resistance to a naturally occurring Rhabdovirus in Drosophila. PLoS Pathogens. [PDF]


Longdon, B, Murray, G, Palmer, WJ, Day, JP, Parker, D, Welch, JJ, Obbard, DJ, Jiggins, FM 2015 The evolution, diversity and host associations of rhabdoviruses. Virus Evolution. 1: vev014. [PDF]

Martinez, J, Ok, S, Smith, S, Snoeck, K, Day, JP and Jiggins, FM 2015 Should Symbionts Be Nice or Selfish? Antiviral Effects of Wolbachia Are Costly but Reproductive Parasitism Is Not. PLoS Pathogens. 11: e1005021. [PDF]

Palmer, WJ and Jiggins, FM 2015 Comparative genomics reveals the origins and diversity of arthropod immune systems. Molecular Biology and Evolution. 32:21112129 [PDF]

Juneja, P, Ariani, CV, Ho, YS, Osei-Poku, J, Palmer, WJ, Pain, A and Jiggins, FM 2015 Exome and Transcriptome Sequencing of Aedes aegypti Identifies a Locus that Confers Resistance to Brugia malayi and Alters the Immune Response. PLoS Pathogens. 11: e1004765. [PDF]

Longdon, B, Hadfield, JD, Day, JP, Smith, SCL, McGonigle, JE, Cogni, R, Cao, C and Jiggins, FM 2015 The causes and consequences of changes in virulence following pathogen host shifts. PLoS Pathogens. 11: e1004728. [PDF]

Ariani, CV, Juneja, P, Smith, S, Tinsley, MC and, Jiggins, FM 2015 Vector competence of Aedes aegypti mosquitoes for filarial nematodes is affected by age and nutrient limitation. Experimental Gerontology. 61:47-53. [PDF]

Ariani, CV, Smith, S, Osei-Poku, J, Short, K, Juneja, P, and, Jiggins, FM 2015 Environmental and genetic factors determine whether the mosquito Aedes aegypti lays eggs without a blood meal. American Journal of Hygiene and Tropical Medicine. 92: 715-721. [PDF]

Ahmed, MZ, Li, SJ, Xue, X, Yin, XJ, Ren, SX, Jiggins, FM, Greeff, JM and Qiu, BL 2015 The Intracellular Bacterium Wolbachia Uses Parasitoid Wasps as Phoretic Vectors for Efficient Horizontal Transmission. PLoS Pathogens. 10: e1004672 [PDF]


Longdon, B, Brockhurst, MA, Russell, CA, Welch, JJ and Jiggins, FM 2014 The Evolution and Genetics of Virus Host Shifts. PLoS Pathogens. 10: e1004395 [PDF]

Martinez, J, Longdon, B, Bauer, S, Chan, Y-S, Miller, WJ, Bourtzis, K, Teixeira, L and Jiggins, FM 2014 Symbionts commonly provide broad spectrum resistance to viruses in insects: a comparative analysis of Wolbachia strains. PLoS Pathogens. 9: e1004369 [PDF]

Quinn, A, Juneja, P and Jiggins, FM 2014 Estimates of allele-specific expression in Drosophila with a single genome sequence and RNA-seq data. Bioinformatics. 30: 2603-2610. [PDF] [PDF supp]

Wilfert, L and Jiggins, FM 2014 Flies on the move: an inherited virus mirrors Drosophila melanogaster's elusive ecology and demography. Molecular Ecology. 23, 20932104 [PDF]

Juneja, P, Osei-Poku, J, Ho, YS, Ariani, CV, Palmer, WJ, Pain, A and Jiggins, FM 2014 Assembly of the Genome of the Disease Vector Aedes aegypti onto a Genetic Linkage Map Allows Mapping of Genes Affecting Disease Transmission. PLoS Neglected Tropical Diseases. 8: e2652 [PDF]

The Strigamia Genome Consortium 2014 Prototypical Arthropod Gene Content and Genome Organisation in the Centipede Strigamia maritima. PLoS Biology. 12: e1002005 [PDF]


Wilfert, L and Jiggins, FM 2013 The dynamics of reciprocal selective sweeps of host resistance and a parasite counter-adaptation in Drosophila. Evolution. 67: 761-773. [PDF]

Chrostek, E, Marialva, MSP, Esteves, SS, Weinert, LA, Martinez, J, Jiggins, FM and Teixeira, L 2013 Wolbachia Variants Induce Differential Protection to Viruses in Drosophila melanogaster: A Phenotypic and Phylogenomic Analysis. PLoS Genetics. 9:e1003896 [PDF]

Longdon B, Cao, C, Martinez, J and Jiggins FM 2013 Previous exposure to an RNA virus does not protect against subsequent infection in Drosophila melanogaster. PLoS One. 8: e73833 [PDF]


Magwire, MM, Fabian, DK, Schweyen, H, Cao, C, Longdon B, Bayer, F and Jiggins, FM 2012 Genome-wide association studies reveal a simple genetic basis of resistance to naturally coevolving viruses in Drosophila. PLoS Genetics. 8: e1003057. [PDF]

Osei-Poku, J, Mbogo, CM, Palmer, WJ and Jiggins, FM 2012 Deep sequencing reveals extensive variation in the gut microbiota of wild mosquitoes from Kenya. Molecular Ecology. 21, 5138-5150. [PDF]

Osei-Poku J, Han C, Mbogo CM and Jiggins FM 2012 Identification of Wolbachia Strains in Mosquito Disease Vectors. PLoS One. 7: e49922. [PDF]

Longdon B and Jiggins FM 2012 Vertically transmitted viral endosymbionts of insects: do sigma viruses walk alone? Proceedings of the Royal Society B. 279: 3889-3898. [PDF]

Obbard, DJ, Maclennan, J, Kim, KW, Rambaut, A, O'Grady, PM and Jiggins, FM 2012 Estimating divergence dates and substitution rates in the Drosophila phylogeny. Molecular Biology and Evolution. 29: 3459-3473. [PDF]

Carpenter, JA, Hadfield, JD, Bangham, J and Jiggins, FM 2012 Specific interactions between host and parasite genotypes do not act as a constraint on the evolution of antiviral resistance in Drosophila. Evolution. 66: 1114-1125. [PDF]

Longdon B, Fabian DK, Hurst GDD and Jiggins FM 2012 Male-killing Wolbachia do not protect Drosophila bifasciata against viral infection. BMC Microbiology. 12(Suppl 1):S8 [PDF]

Longdon B, Wilfert L and Jiggins FM 2012 The Sigma viruses of Drosophila. In: Rhabdoviruses: Molecular Taxonomy, Evolution, Genomics, Ecology, Cytopathology and Control, edited by Ralf Dietzgen and Ivan Kuzmin. Caister Academic Press. [PDF]

Richardson, MF, Weinert, LA, Welch, JJ, Linheiro, RS, Magwire, MM, Jiggins, FM and Bergman, CM 2012 Population genomics of the Wolbachia endosymbiont in Drosophila melanogaster. PLoS Genetics. 8: e1003129. [PDF]

The Heliconius Genome Consortium 2012 Butterfly genome reveals promiscuous exchange of mimicry adaptations among species. Nature. 487:94-98 [PDF]


Longdon, B, Hadfield, JD, Webster, CL, Obbard, DJ and Jiggins, FM 2011 Host phylogeny determines viral persistence and replication in novel hosts. PLoS Pathogens. e1002260. [PDF]

Magwire, MM, Bayer, F, Webster, CL, Cao, C and Jiggins, FM 2011 Successive Increases in the Resistance of Drosophila to Viral Infection through a Transposon Insertion Followed by a Duplication. PLoS Genetics. 7: e1002337. [PDF]

Longdon, B, Wilfert, L, Osei-Poku, J, Cagney, H, Obbard, DJ and Jiggins, FM 2011 Host-switching by a vertically-transmitted rhabdovirus in Drosophila. Biology Letters. 7: 747-750 [PDF]

Wilfert, L, Longdon, B, Ferreira, AGA, Bayer, F and Jiggins, FM 2011 Trypanosomatids are common and diverse parasites of Drosophila. Parasitology. 138, 858-865. [PDF]

Longdon, B, Wilfert, L, Obbard, DJ and Jiggins, FM 2011 Rhabdoviruses in Two Species of Drosophila: Vertical Transmission and a Recent Sweep. Genetics. 188: 141-150. [PDF]

Wells, PM, Baverstock, J, Majerus, MEN, Jiggins, FM, Roy, HE,and Pell, JK 2011 The effect of the coccinellid Harmonia axyridis (Coleoptera: Coccinellidae) on transmission of the fungal pathogen Pandora neoaphidis (Entomophthorales: Entomophthoraceae). Eur. J. Entomol. 108: 87-90 [PDF]

Michie, LJ, Masson, A, Ware, R and Jiggins, FM 2011 Seasonal phenotypic plasticity: wild ladybirds are darker at cold temperatures. Evolutionary Ecology. 25: 1259-1268. [PDF]

Jiggins, FM and Hurst, GDD 2011 Rapid insect evolution by symbiont transfer. Science. 332: 185-186 [PDF]


Obbard, DJ, Jiggins, FM, Bradshaw, NJ and Little, TJ 2010 Recent and recurrent selective sweeps of the antiviral RNAi gene Argonaute-2 in three species of Drosophila. Molecular Biology and Evolution. 28: 1043-1056 [PDF]

Michie, LJ, Mallard, F, Majerus MEN and Jiggins FM 2010 Melanic through nature or nurture: genetic polymorphism and phenotypic plasticity in Harmonia axyridis. Journal of Evolutionary Biology. 23: 1699-1707 [PDF]

Longdon, B and Jiggins, FM 2010 Paternally transmitted parasites. Current Biology. 20: R695-R696 [PDF]

Wilfert, L and Jiggins, FM 2010 Disease association mapping in Drosophila can be replicated in the wild. Biology Letters. 6: 666-668. [PDF]

Wilfert, L and Jiggins, FM 2010 Host-parasite coevolution: genetic variation in a virus population and the interaction with a host gene. Journal of Evolutionary Biology. 23: 1447-1455 [PDF]

Rhule, EL, Majerus, MEN, Jiggins, FM and Ware, RL 2010 Potential role of the sexually transmitted mite Coccipolipus hippodamiae in controlling populations of the invasive ladybird Harmonia axyridis. Biological Control. 53: 243-247 [PDF]


Carpenter, JA, Keegan, L, Wilfert, L, O'Connell, MA and Jiggins, FM 2009 Evidence for ADAR-induced hypermutation of the Drosophila sigma virus (Rhabdoviridae). BMC Genetics. 10, 75. [PDF]

Obbard, DJ, Welch, JJ, Kim, K-W, and Jiggins, FM 2009 Quantifying Adaptive Evolution in the Drosophila Immune System. PLoS Genetics. 5: e1000698. [PDF]

Longdon, B, Obbard, DJ & Jiggins, FM 2009 Sigma viruses from three species of Drosophila form a major new clade in the rhabdovirus phylogeny. Proceedings of the Royal Society B. 277: 35-44 [PDF]

Carpenter, J., Hutter, S., Baines, J. F., Roller, J., Saminadin-Peter, S. S., Parsch, J. & Jiggins, F. M. 2009 The Transcriptional Response of Drosophila melanogaster to Infection with the Sigma Virus (Rhabdoviridae). PLoS ONE 4, e6838. [PDF]

Weinert, LA, Welch, JJ, & Jiggins, FM 2009 Conjugation genes are common throughout the genus Rickettsia and are transmitted horizontally. Proceedings of the Royal Society B. 276: 3601-3610 [PDF]

Weinert, LA, Werren, JH, Aebi, A, Stone, GN & Jiggins, FM 2009 Evolution and diversity of Rickettsia bacteria. BMC Biology 7: 6 [PDF]

Obbard, D.J. Gordon, K.H.J., Buck, A.H., and Jiggins, F.M. 2009 The evolution of RNAi as a defence against viruses and transposable elements. Philosophical Transactions of the Royal Society. 364: 99-115 [PDF]

Before 2009

Bangham, J., Knott, S.A. Kim, K.-W., Young R.S., and Jiggins, F.M. 2008 Genetic variation affecting host-parasite interactions: major-effect quantitative trait loci affect the transmission of sigma virus in Drosophila melanogaster. Molecular Ecology. 17: 3800-3807.[PDF]

Bangham J, Kim KW, Webster C, Jiggins FM 2008 Genetic variation affecting host-parasite interactions: different genes affect different aspects of sigma virus replication and transmission in Drosophila melanogaster. Genetics. 178:2191-2199. [PDF]

Weinert LA, Tinsley MC, Temperley M, Jiggins FM 2008 Are we underestimating the diversity and incidence of insect bacterial symbionts? A case study in ladybird beetles. Biology Letters. 3: 678-681 [PDF]

Obbard, DJ, Callister, DM, Jiggins, FM, Soares, DC, Yan, G, Little, T J 2008 The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae. BMC Evolutionary Biology 8, 274. [PDF]

Bangham J, Obbard DJ, Kim KW, Haddrill PR, Jiggins FM 2007 The age and evolution of an antiviral resistance mutation in Drosophila melanogaster. Proceedings of the Royal Society B. 274: 2027-2034 [PDF]

Jiggins FM, Kim KW, 2007 A screen for immunity genes evolving under positive selection in Drosophila. Journal of Evolutionary Biology. 20: 965-970 [PDF]

Obbard DJ, Linton YM, Jiggins FM, Yan G, Little TJ 2007 Population genetics of Plasmodium resistance genes in Anopheles gambiae: no evidence for strong selection. Molecular Ecology. 16: 3497-3510 [PDF]

Carpenter, J, Obbard, DJ, Maside, X, and Jiggins, FM 2007 The recent spread of a vertically transmitted virus through populations of Drosophila melanogaster. Molecular Ecology. 16: 3947-3954 [PDF]

Bangham, J, Jiggins, FM, and Lemaitre, B 2006 Insect Immunity: The Post-Genomic Era. Immunity 25: 1-5. [PDF]

Jiggins, FM, and Kim KW 2006 Contrasting evolutionary patterns in Drosophila immune receptors. J. Mol. Evol. 63: 769-780. [PDF]

Obbard, DJ, Jiggins, FM, Halligan, DL and Little TJ 2006 Natural Selection Drives Extremely Rapid Evolution in Antiviral RNAi Genes. Current Biology 16: 580-585. [PDF]

Jiggins, FM 2006 Adaptive evolution and recombination of Rickettsia antigens. J. Mol. Evol. 62: 99-110 [PDF]

Tinsley, MT, Blanford, S and Jiggins, FM 2006 Genetic variation in the Drosophila melanogaster immune response. Parasitology. 132: 767-773 [PDF]

Jiggins, FM and Kim KW 2005 The evolution of antifungal peptides in Drosophila. Genetics. 171: 1847-1859 [PDF]

Jiggins, FM and Tinsley, MT 2005 An ancient mitochondrial polymorphism linked to a sex ratio distorting bacterium. Genetics. 171: 1115-1124 [PDF]

Hurst, GDD and Jiggins, FM 2005 Problems with mitochondrial DNA as a marker in population, phylogeographic and phylogenetic studies: the effects of inherited symbionts. Proc. R. Soc. Lond. B 272: 1525-1534. [PDF]

Jiggins, FM 2003 Male-killing Wolbachia and mitochondrial DNA: selective sweeps, hybrid introgression and parasite population dynamics. Genetics 164: 5-12. [PDF]

Jiggins, FM and Hurst, GDD 2003 The evolution of parasite recognition genes in the innate immune system: purifying selection on Drosophila melanogaster peptidoglycan recognition proteins. J. Mol. Evol. 57: 598-605. [PDF]

Hurst, G. D. D., F. M. Jiggins and M. E. N. Majerus, 2003 Inherited microorganisms that selectively kill male hosts: the hidden players of insect evolution? in Insect symbiosis, edited by K. Bourtzis and T. A. Miller. RC Press, Boca Raton. [PDF]

Keeling, M. J., F. M. Jiggins and J. M. READ, 2003 The invasion and coexistence of competing Wolbachia strains. Heredity 91: 382-388. [PDF]

Dobson, S. L., C. W. Fox and F. M. Jiggins , 2002 The effect of Wolbachia-induced cytoplasmic incompatibility on host population size in natural and manipulated systems. Proc. R. Soc. Lond. B 269: 437-445. [PDF]

Jiggins , F. M., J. K. Bentley, M. E. N. Majerus and G. D. D. Hurst, 2002 Recent changes in phenotype and patterns of host specialisation in Wolbachia bacteria. Molecular Ecology 11: 1275-1283. [PDF]

Jiggins , F. M., 2002 The rate of recombination in Wolbachia bacteria. Mol. Biol. Evol. 19: 1640-1643. [PDF]

Jiggins , F. M., J. P. Randerson, G. D. D. Hurst and M. E. N. Majerus, 2002 How can sex ratio distorters reach extreme prevalences? A natural population in which male-killing Wolbachia have near-perfect vertical transmission efficiency and are not suppressed. Evolution 56: 2290-2295. [PDF]

Jiggins , F. M., G. D. D. Hurst and Z. Yang, 2002 Host-symbiont conflicts: positive selection on the outer membrane protein of parasitic but not mutualistic Rickettsiaceae. Mol. Biol. Evol. 19: 1341-1349. [PDF]

Hurst, G. D. D., F. M. Jiggins and A. Pomiankowski, 2002 Which way to manipulate reproduction? Wolbachia that cause cytoplasmic incompatibility are easily invaded by sex ratio distorting mutants. Am. Nat. 160: 360-373. [PDF]

Jiggins, F. M., Bentley, M. E. N. Majerus and G. D. D. Hurst, 2001 How many species are infected with Wolbachia? Cryptic sex ratio distorters revealed to be common by intensive sampling. Proc. R. Soc. Lond. B 268: 1123-1126. [PDF]

Jiggins , F. M., G. D. D. Hurst, J. H. G. V. d. Schulenburg and M. E. N. Majerus, 2001 Two male-killing Wolbachia strains coexist within a population of the butterfly Acraea encedon. Heredity 86: 161-166. [PDF]

Jiggins , F. M., J. H. G. V. d. Schulenburg, G. D. D. Hurst and M. E. N. Majerus, 2001 Recombination confounds interpretations of Wolbachia evolution. Proc. R. Soc. Lond. B 268: 1423-1427. [PDF]

Hurst, G. D. D., F. M. Jiggins and S. J. W. Robinson, 2001 What causes inefficient transmission of male-killing Wolbachia in Drosophila? Heredity 87: 220-226. [PDF]

Jiggins , F. M., G. D. D. Hurst, C. E. Dolman and M. E. N. Majerus, 2000 High prevalence male-killing Wolbachia in the butterfly Acraea encedana. J. Evol. Biol. 13: 495-501. [PDF]

Jiggins , F. M., G. D. D. Hurst and M. E. N. Majerus, 2000 Sex ratio distorting Wolbachia cause sex role reversal in their butterfly hosts. Proc. R. Soc. Lond. B 267: 69-73. [PDF]

Jiggins , F. M., G. D. D. Hurst, C. D. Jiggins, J. H. G. V. d. Schulenburg and M. E. N. Majerus, 2000 The butterfly Danaus chrysippus is host to a male-killing Spiroplasma bacterium. Parasitology 120: 439-446. [PDF]

Randerson, J. P., F. M. Jiggins and L. D. Hurst, 2000 Male-killing can select for male mate choice: a novel solution to the paradox of the lek. Proc. R. Soc. Lond. B 267: 867-874. [PDF]

Hurst, G. D. D., and F. M. Jiggins, 2000 Male-killing bacteria in insects: mechanisms, incidence, and implications. Emerging Infect. Dis. 6: 329-336. [PDF]

Jiggins, F. M., G. D. D. Hurst and M. E. N. Majerus, 1999 How common are meiotically driving sex chromosomes in insects? Am. Nat. 154: 481-483. [PDF]

Hurst, G. D. D., F. M. Jiggins, J. H. G. Schulenburg, D. Bertrand, S. A. West et al., 1999 Male-killing Wolbachia in two species of insect. Proc. R. Soc. Lond. B 266: 735-740. [PDF]

Jiggins, F. M., G. D. D. Hurst and M. E. N. Majerus, 1998 Sex ratio distortion in Acraea encedon (Lepidoptera: Nymphalidae) is caused by a male-killing bacterium. Heredity 81: 87-91. [PDF]